Gene Expression Profiling of Cells, Tissues, and Developmental Stages of the Nematode C. elegans

  1. S.J. MCKAY,
  2. R. JOHNSEN,
  3. J. KHATTRA,
  4. J. ASANO,
  5. D.L. BAILLIE,
  6. S. CHAN,
  7. N. DUBE,
  8. L. FANG,
  9. B. GOSZCZYNSKI,
  10. E. HA,
  11. E. HALFNIGHT,
  12. R. HOLLEBAKKEN,
  13. P. HUANG,
  14. K. HUNG,
  15. V. JENSEN,
  16. S.J.M. JONES,
  17. H. KAI,
  18. D. LI,
  19. A. MAH,
  20. M. MARRA,
  21. J. MCGHEE,
  22. R. NEWBURY,
  23. A. POUZYREV,
  24. D.L. RIDDLE,
  25. E. SONNHAMMER,
  26. H. TIAN,
  27. D. TU,
  28. J.R. TYSON,
  29. G. VATCHER,
  30. A. WARNER,
  31. K. WONG,
  32. Z. ZHAO, and
  33. D.G. MOERMAN
  1. *Genome Sciences Centre, BC Cancer Agency, Vancouver, B.C., Canada, V6T 1Z4; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, B.C., Canada, V5A 1S6; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada T2N 4N1; Department of Zoology, University of British Columbia, Vancouver, B.C., Canada V6T 1Z4; §Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211-7400; **Karolinska Institute, Stockholm, Sweden

This extract was created in the absence of an abstract.

Excerpt

Completion of the DNA sequences of the humangenome and that of the nematode Caenorhabditis elegansallows the large-scale identification and analysis of orthologs of human genes in an organism amenable to detailed genetic and molecular analyses. We are determining gene expression profiles in specific cells, tissues, anddevelopmental stages in C. elegans. Our ultimate goal isnot only to describe detailed gene expression profiles, butalso to gain a greater understanding of the organization ofgene regulatory networks and to determine how they control cell function during development and differentiation...

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