Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
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Antiviral Amentoflavone from Selaginella sinensis
Shuang-Cheng MA, Paul Pui-Hay BUT, Vincent Eng-Choon OOI, Yue-Hua HE, Spencer Hon-Sun LEE, Song-Fong LEE, Rui-Chao LIN
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Keywords: Selaginella sinensis, amentoflavone, anti-RSV activity, HPLC
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2001 Volume 24 Issue 3 Pages 311-312

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Abstract

Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 μg/ml. The contents of amentoflavone in nine species of Selaginella were determined by reversed-phase HPLC. S. sinensis showed a higher content of 1.13%.

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© 2001 The Pharmaceutical Society of Japan
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