Intravascular hemolysis in aluminium phosphide poisoning

Am J Emerg Med. 1999 Sep;17(5):488-9. doi: 10.1016/s0735-6757(99)90255-3.

Abstract

Intravascular hemolysis is most often secondary to exposure to a variety of drugs or infections, and usually occurs in patients who are deficient in glucose-6-phosphate dehydrogenase (G-6-PD) enzyme. Aluminium phosphide, a fumigant widely used in India, has been reported to produce intravascular hemolysis in only one patient who also had concomitant G-6-PD deficiency. This report describes the occurrence of intravascular hemolysis with aluminium phosphide poisoning in a patient with normal G-6-PD levels. This is of significance as jaundice in patients with this poisoning is often attributed to hepatic damage alone.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aluminum Compounds / poisoning*
  • Hemolysis*
  • Humans
  • India
  • Jaundice / etiology
  • Male
  • Pesticides / poisoning*
  • Phosphines / poisoning*

Substances

  • Aluminum Compounds
  • Pesticides
  • Phosphines
  • aluminum phosphide