GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology

J Med Chem. 2000 Apr 20;43(8):1427-47. doi: 10.1021/jm9904349.

Authors

M Chebib¹, G A Johnston

Affiliation

¹ Adrien Albert Laboratory of Medicinal Chemistry, Department of Pharmacology, University of Sydney, Sydney, New South Wales 2006, Australia.

PMID: 10780899
DOI: 10.1021/jm9904349

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Excitatory Amino Acid Agonists / chemistry*
Excitatory Amino Acid Agonists / pharmacology
Excitatory Amino Acid Antagonists / chemistry*
Excitatory Amino Acid Antagonists / pharmacology
Humans
Ion Channel Gating*
Ion Channels / agonists*
Ligands
Receptors, GABA / drug effects
Receptors, GABA / genetics
Receptors, GABA / physiology
Receptors, GABA-A / drug effects
Receptors, GABA-A / genetics
Receptors, GABA-A / physiology
Structure-Activity Relationship
gamma-Aminobutyric Acid / physiology*

Substances

Excitatory Amino Acid Agonists
Excitatory Amino Acid Antagonists
GABA-C receptor
Ion Channels
Ligands
Receptors, GABA
Receptors, GABA-A
gamma-Aminobutyric Acid