Abstract
Flagellin, the main protein of the bacterial flagella, elicits defence responses and alters growth in Arabidopsis seedlings. Previously, we identified the FLS1 locus, which confers flagellin insensitivity in Ws-0. To identify additional components involved in flagellin perception, we screened for flagellin insensitivity mutants in the flagellin-sensitive accession La-er. Here, we describe the identification of a new locus, FLS2, by a map-based strategy. The FLS2 gene is ubiquitously expressed and encodes a putative receptor kinase. FLS2 shares structural and functional homologies with known plant resistance genes and with components involved in the innate immune system of mammals and insects.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Arabidopsis / drug effects*
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Arabidopsis / enzymology*
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Arabidopsis / genetics
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Arabidopsis / growth & development
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Arabidopsis Proteins*
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Cloning, Molecular
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Flagellin / pharmacology*
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Gene Expression Profiling
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Genes, Plant / genetics
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Genetic Complementation Test
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Leucine-Rich Repeat Proteins
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Membrane Proteins / chemistry
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Membrane Proteins / genetics
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Membrane Proteins / metabolism
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Molecular Sequence Data
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Mutation / genetics
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Phenotype
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Plant Proteins / chemistry
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Plant Proteins / genetics
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Plant Proteins / metabolism
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Plants, Genetically Modified
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Protein Kinases / chemistry
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Protein Kinases / genetics
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Protein Kinases / metabolism*
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Proteins / chemistry
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Proteins / genetics
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Proteins / metabolism*
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Respiratory Burst
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Signal Transduction / drug effects
Substances
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Arabidopsis Proteins
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Leucine-Rich Repeat Proteins
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Membrane Proteins
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Plant Proteins
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Proteins
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RNA, Messenger
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Flagellin
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Protein Kinases
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FLS2 protein, Arabidopsis