The effects of moderate alcohol consumption on female hormone levels and reproductive function

Alcohol Alcohol. 2000 Sep-Oct;35(5):417-23. doi: 10.1093/alcalc/35.5.417.

Abstract

Studies that have investigated the effect of moderate alcohol consumption on the level of oestrogens and progesterone in both pre- and post-menopausal women are reviewed. It is concluded that several lines of evidence point to an alcohol-induced rise in natural or synthetic oestrogen levels in women. Proposed mechanisms include an increased rate of aromatization of testosterone or a decreased rate of oxidation of oestradiol to oestrone. Moderate alcohol consumption has also been linked to decreased progesterone levels in pre-menopausal women. The relevance of these findings to female health, fertility and the timing of the menopause is considered.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking / metabolism*
  • Estrogens / metabolism*
  • Female
  • Fertility / physiology*
  • Gonadal Steroid Hormones / metabolism
  • Humans
  • Menopause / metabolism*
  • Postmenopause / metabolism
  • Premenopause / metabolism
  • Progesterone / metabolism*

Substances

  • Estrogens
  • Gonadal Steroid Hormones
  • Progesterone