Abstract
We have identified a new member of the spalt-like gene family in mice, msal-3. We compared the expression patterns of msal-3 and msal-1 during development and show that they exhibit overlapping yet exclusive patterns of expression in the developing forebrain, diencephalon, midbrain/hindbrain boundary and spinal cord. Both genes are expressed from E7 in opposite gradients in primitive streak mesoderm. Subsequently their transcripts are localized to regions of mesenchyme/epithelial interaction in the palate, heart, limbs, anal and urogenital region.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Carrier Proteins / biosynthesis*
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Central Nervous System / embryology*
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DNA-Binding Proteins*
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Diencephalon / embryology
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Embryo, Mammalian / metabolism
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Epithelium / embryology*
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Homeodomain Proteins / biosynthesis*
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In Situ Hybridization
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Mesencephalon / embryology
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Mesoderm / metabolism*
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Mice
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Molecular Sequence Data
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Nerve Tissue Proteins / biosynthesis*
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Neurons / metabolism
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Olfactory Bulb / embryology
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Prosencephalon / embryology
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Rhombencephalon / embryology
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Spinal Cord / embryology
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Time Factors
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Tissue Distribution
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Transcription Factors / biosynthesis
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Xenopus Proteins*
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Zinc Fingers
Substances
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Carrier Proteins
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DNA-Binding Proteins
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Homeodomain Proteins
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Nerve Tissue Proteins
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Sall1 protein, mouse
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Sall3 protein, mouse
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Transcription Factors
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Xenopus Proteins
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sal1-A protein, Xenopus
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spalt protein, vertebrate