Cell movements during vertebrate development: integrated tissue behaviour versus individual cell migration

Curr Opin Genet Dev. 2001 Aug;11(4):464-9. doi: 10.1016/s0959-437x(00)00218-5.

Abstract

Cell migration during development is fundamental to the establishment of the embryonic architecture. Depending on the context, cells may move either as integrated sheets of tissue or individually. Recently, molecules that are involved in both these types of cell behaviour have been identified, helping us to understand developmental processes as important as gastrulation and neural crest formation, and ultimately, the morphogenetic movements that shape the embryo.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Movement / physiology*
  • Gastrula / physiology
  • Mesoderm / cytology
  • Mesoderm / physiology*
  • Neural Crest / cytology
  • Neural Crest / embryology*
  • Neural Crest / physiology
  • Signal Transduction