Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions

Cell. 2002 Apr 19;109(2):145-8. doi: 10.1016/s0092-8674(02)00718-3.

Abstract

Small nucleolar RNAs represent an abundant, evolutionarily ancient group of noncoding RNAs which possess impressively diverse functions ranging from 2'-O-methylation and pseudouridylation of various classes of RNAs, through nucleolytic processing of rRNAs to the synthesis of telomeric DNA.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain Chemistry / genetics
  • Cell Nucleolus / genetics*
  • Evolution, Molecular
  • Gene Expression Regulation / genetics*
  • Humans
  • Methylation
  • RNA, Small Nucleolar / genetics*
  • Telomerase / genetics
  • Transcription, Genetic / genetics*
  • UDPglucose-Hexose-1-Phosphate Uridylyltransferase / genetics

Substances

  • RNA, Small Nucleolar
  • UDPglucose-Hexose-1-Phosphate Uridylyltransferase
  • Telomerase