Advances in structure analysis using small-angle scattering in solution

Curr Opin Struct Biol. 2002 Oct;12(5):654-60. doi: 10.1016/s0959-440x(02)00363-9.

Abstract

The resolution and reliability of solution scattering models have been significantly improved by ab initio shape and domain structure determination, and by detailed modelling of macromolecular complexes using rigid-body refinement. Substantial progress has also been made in the quantitative analysis and modelling of assembly and folding processes, and intermolecular interactions.

Publication types

  • Review

MeSH terms

  • Models, Molecular
  • Molecular Conformation*
  • Molecular Structure*
  • Neutrons
  • Protein Conformation
  • Proteins / chemistry
  • Scattering, Radiation*
  • Solutions
  • X-Rays

Substances

  • Proteins
  • Solutions