Cell cycle and cell fate interactions in neural development

Curr Opin Neurobiol. 2003 Feb;13(1):26-33. doi: 10.1016/s0959-4388(03)00005-9.

Abstract

Mechanisms coupling cell cycle and cell fate operate at different steps during neural development. Intrinsic factors control the cell proliferation of distinct brain regions and changes of cell fate competence, whereas components of the cell cycle machinery could play a major role in setting the appropriate timing of the generation of different cell types.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Cycle / physiology*
  • Cell Differentiation / physiology*
  • Cell Lineage / physiology*
  • Central Nervous System / cytology
  • Central Nervous System / embryology*
  • Central Nervous System / physiology
  • Gene Expression Regulation, Developmental / genetics
  • Humans
  • Neurons / cytology*
  • Neurons / physiology
  • Signal Transduction / genetics
  • Stem Cells / cytology*
  • Stem Cells / physiology
  • Vertebrates / embryology*
  • Vertebrates / genetics