Abstract
By the acute stage of HIV-1 infection, the immune system already faces daunting challenges. Research on mucosal barriers and the events immediately after heterosexual transmission that precede this acute stage could facilitate the development of effective microbicides and vaccines.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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AIDS Vaccines / pharmacology
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Acute Disease
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Animals
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CD4-Positive T-Lymphocytes / immunology
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CD4-Positive T-Lymphocytes / virology
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Female
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HIV Infections / immunology
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HIV Infections / prevention & control*
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HIV Infections / transmission*
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HIV-1 / pathogenicity*
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Humans
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Male
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Menstrual Cycle
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Mucous Membrane / physiology
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Mucous Membrane / virology*
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Semen / virology
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Simian Acquired Immunodeficiency Syndrome / transmission
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Simian Immunodeficiency Virus / pathogenicity
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Vagina / physiology
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Vagina / virology