Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism

Org Biomol Chem. 2003 May 7;1(9):1452-4. doi: 10.1039/b302098c.

Abstract

Hydrogen transfer from artepillin C to cumylperoxyl radical proceeds via one-step hydrogen atom transfer rather than via electron transfer, the rate constant of which is comparable to that of (+)-catechin, indicating that artepillin C can act as an efficient antioxidant.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catechin / chemistry
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / pharmacology
  • Free Radicals / antagonists & inhibitors
  • Free Radicals / chemistry
  • Hydrogen / chemistry
  • Kinetics
  • Nucleic Acid Synthesis Inhibitors
  • Peroxides / antagonists & inhibitors
  • Peroxides / chemistry
  • Phenylpropionates / chemistry*
  • Phenylpropionates / pharmacology*
  • Propolis / chemistry*

Substances

  • Free Radical Scavengers
  • Free Radicals
  • Nucleic Acid Synthesis Inhibitors
  • Peroxides
  • Phenylpropionates
  • perhydroxyl radical
  • artepillin C
  • Hydrogen
  • Catechin
  • Propolis