Abstract
Recently a number of viruses, including a poxvirus, herpesvirus, retrovirus and two paramyxoviruses, have been shown to activate cells via Toll-like receptor family members. Here we postulate that although activation via Toll-like receptor molecules can lead to anti-viral innate immune responses, in some cases viruses may use these responses to ameliorate infection.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Cytokines / physiology
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Humans
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Immune System / immunology*
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Immunity, Innate / physiology*
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Infection Control
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Infections / immunology
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Infections / virology
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Membrane Glycoproteins / physiology*
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Receptors, Cell Surface / immunology
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Receptors, Cell Surface / physiology*
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Signal Transduction / physiology*
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Toll-Like Receptors
Substances
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Cytokines
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Membrane Glycoproteins
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Receptors, Cell Surface
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Toll-Like Receptors