Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast

Nat Rev Microbiol. 2004 Mar;2(3):203-16. doi: 10.1038/nrmicro843.

Authors

Stuart A Ralph¹, Giel G van Dooren, Ross F Waller, Michael J Crawford, Martin J Fraunholz, Bernardo J Foth, Christopher J Tonkin, David S Roos, Geoffrey I McFadden

Affiliation

¹ Institut Pasteur, Biology of Host-Parasite Interactions, 25 Rue du Docteur Roux, 75724, Paris, Cedex 15, France.

PMID: 15083156
DOI: 10.1038/nrmicro843

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Antimalarials / therapeutic use
Energy Metabolism
Fatty Acids / biosynthesis
Heme / biosynthesis
Hemiterpenes / biosynthesis
Host-Parasite Interactions
Humans
Malaria, Falciparum / drug therapy
Malaria, Falciparum / parasitology
Models, Biological
Organelles / metabolism*
Organelles / ultrastructure
Organophosphorus Compounds
Plasmodium falciparum / metabolism*
Plasmodium falciparum / pathogenicity
Plasmodium falciparum / ultrastructure
Protozoan Proteins / metabolism

Substances

Antimalarials
Fatty Acids
Hemiterpenes
Organophosphorus Compounds
Protozoan Proteins
isopentenyl pyrophosphate
Heme