A genome-wide and nonredundant mouse transcription factor database

Mutsumi Kanamori; Hideaki Konno; Naoki Osato; Jun Kawai; Yoshihide Hayashizaki; Harukazu Suzuki

doi:10.1016/j.bbrc.2004.07.179

A genome-wide and nonredundant mouse transcription factor database

Biochem Biophys Res Commun. 2004 Sep 24;322(3):787-93. doi: 10.1016/j.bbrc.2004.07.179.

Authors

Mutsumi Kanamori¹, Hideaki Konno, Naoki Osato, Jun Kawai, Yoshihide Hayashizaki, Harukazu Suzuki

Affiliation

¹ Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences Center (GSC), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

PMID: 15336533
DOI: 10.1016/j.bbrc.2004.07.179

Abstract

Here we describe the development of a genome-wide and nonredundant mouse transcription factor database and its viewer (http://genome.gsc.riken.gp/TFdb/). We systematically selected transcription factors with DNA-binding properties and their regulators on the basis of their LocusLink and Gene Ontology annotations. We also incorporated into our database information regarding the corresponding available cDNA clones and their structural properties. Because of these features, our database is unique and may provide useful information for systematic genome-wide studies of transcriptional regulation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
DNA-Binding Proteins / genetics
Databases, Nucleic Acid
Gene Expression Regulation / genetics
Mice / genetics*
Transcription Factors / genetics*
Transcription, Genetic / genetics*

Substances

DNA-Binding Proteins
Transcription Factors