Genome duplication led to highly selective expansion of the Arabidopsis thaliana proteome

Cathal Seoighe; Chris Gehring

doi:10.1016/j.tig.2004.07.008

Genome duplication led to highly selective expansion of the Arabidopsis thaliana proteome

Trends Genet. 2004 Oct;20(10):461-4. doi: 10.1016/j.tig.2004.07.008.

Authors

Cathal Seoighe¹, Chris Gehring

Affiliation

¹ South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa. cathal@science.uct.ac.za

PMID: 15363896
DOI: 10.1016/j.tig.2004.07.008

Abstract

Multiple ancient genome duplications in Arabidopsis thaliana provide unique opportunities to assess factors that influence the fates of duplicated genes. We have found that genes retained in duplicate following one round of genome duplication are significantly more likely to be retained in duplicate again after a subsequent genome duplication. Genes retained in duplicate form a functionally biased set and include a significant over-representation of genes involved in the regulation of transcription.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Arabidopsis / genetics*
Arabidopsis Proteins / genetics*
Evolution, Molecular*
Gene Duplication*
Gene Order
Genes, Duplicate / genetics*
Genome, Plant*
Proteome / genetics*

Substances

Arabidopsis Proteins
Proteome