PatchDock and SymmDock: servers for rigid and symmetric docking

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W363-7. doi: 10.1093/nar/gki481.

Abstract

Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein-protein and protein-small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at http://bioinfo3d.cs.tau.ac.il. The methods behind the servers are very efficient, allowing large-scale docking experiments.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Internet
  • Ligands
  • Multiprotein Complexes / chemistry*
  • Protein Conformation
  • Software*
  • User-Computer Interface

Substances

  • Ligands
  • Multiprotein Complexes