Abstract
To assess short- and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years). Fifty-three percent of patients were seizure free at 10 years. The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.
MeSH terms
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Anterior Temporal Lobectomy / statistics & numerical data*
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Anticonvulsants / therapeutic use
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Chronic Disease
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Epilepsy / diagnosis*
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Epilepsy / drug therapy
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Epilepsy / epidemiology
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Epilepsy / surgery*
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Humans
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Incidence
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Outcome Assessment, Health Care / methods*
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Prognosis
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Proportional Hazards Models*
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Reproducibility of Results
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Retrospective Studies
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Risk Assessment / methods*
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Risk Factors
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Secondary Prevention
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Sensitivity and Specificity
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Severity of Illness Index*
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Temporal Lobe / surgery
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Treatment Failure
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Treatment Outcome
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United States / epidemiology