Abstract
The Lon ATP-dependent protease plays a major role in protein quality control. An increasing number of regulatory proteins, however, are being identified as Lon substrates, thus indicating that in addition to its housekeeping function, Lon plays an important role in regulating many biological processes in bacteria. This review presents and discusses the involvement of Lon in different aspects of bacterial physiology, including cell differentiation, sporulation, pathogenicity and survival under starvation conditions.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Bacillus subtilis / enzymology
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Bacterial Physiological Phenomena*
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Bacterial Proteins / physiology*
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Cell Differentiation
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Cell Division
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DNA Methylation
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Enzyme Activation
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Escherichia coli / enzymology
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Gene Expression Regulation, Bacterial
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Gene Expression Regulation, Enzymologic
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Protease La / physiology*
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Salmonella typhimurium / enzymology
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Signal Transduction
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Spores, Bacterial / enzymology
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Substrate Specificity
Substances
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Bacterial Proteins
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Protease La