Abstract
We present the Saccharomyces cerevisiae PeptideAtlas composed from 47 diverse experiments and 4.9 million tandem mass spectra. The observed peptides align to 61% of Saccharomyces Genome Database (SGD) open reading frames (ORFs), 49% of the uncharacterized SGD ORFs, 54% of S. cerevisiae ORFs with a Gene Ontology annotation of 'molecular function unknown', and 76% of ORFs with Gene names. We highlight the use of this resource for data mining, construction of high quality lists for targeted proteomics, validation of proteins, and software development.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Codon
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Databases, Protein*
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Genes, Fungal
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Hydrophobic and Hydrophilic Interactions
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Mass Spectrometry
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Molecular Weight
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Open Reading Frames / genetics
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Peptides / chemistry
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Peptides / metabolism*
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Proteome / chemistry
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Proteome / genetics
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Proteome / metabolism*
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Saccharomyces cerevisiae / chemistry
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism*
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Saccharomyces cerevisiae Proteins / chemistry
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism*
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User-Computer Interface
Substances
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Codon
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Peptides
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Proteome
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Saccharomyces cerevisiae Proteins