Abstract
Focal areas of restricted diffusion adjacent to high-grade glioma resection cavities were detected in 70% of patients on immediate postoperative MRI studies. Follow-up studies demonstrated cystic encephalomalacia in 91% of these foci, suggesting the presence of infarction, and the infarcted tissue demonstrated enhancement in 43% of cases. New postoperative deficits correlated well with the anatomic region of infarction in six patients. Enhancement in perioperative infarcts can mimic tumor progression on follow-up imaging studies.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Brain / blood supply
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Brain / pathology
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Brain / physiopathology
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Brain Infarction / etiology*
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Brain Infarction / pathology*
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Brain Infarction / physiopathology
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Brain Neoplasms / blood supply
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Brain Neoplasms / physiopathology
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Brain Neoplasms / surgery*
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Cerebral Arteries / injuries
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Cerebral Arteries / pathology
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Cerebral Arteries / physiopathology
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Cerebrovascular Circulation / physiology
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Confusion / etiology
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Confusion / pathology
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Confusion / physiopathology
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Diffusion Magnetic Resonance Imaging / standards
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Female
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Glioblastoma / blood supply
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Glioblastoma / physiopathology
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Glioblastoma / surgery*
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Humans
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Male
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Microcirculation / injuries
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Microcirculation / pathology
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Microcirculation / physiopathology
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Middle Aged
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Neurosurgical Procedures / adverse effects*
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Paresis / etiology
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Paresis / pathology
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Paresis / physiopathology
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Postoperative Complications / etiology*
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Postoperative Complications / pathology*
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Postoperative Complications / physiopathology
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Predictive Value of Tests