Higher-order structures of chromatin: the elusive 30 nm fiber

Cell. 2007 Feb 23;128(4):651-4. doi: 10.1016/j.cell.2007.02.008.

Abstract

Despite progress in understanding chromatin function, the structure of the 30 nm chromatin fiber has remained elusive. However, with the recent crystal structure of a short tetranucleosomal array, the 30 nm fiber is beginning to come into view.

Publication types

  • Review

MeSH terms

  • Animals
  • Binding Sites
  • Chromatin / chemistry
  • Chromatin / genetics
  • Chromatin / ultrastructure*
  • DNA / chemistry
  • DNA / genetics
  • DNA / ultrastructure*
  • Evolution, Molecular
  • Histones / chemistry
  • Histones / genetics
  • Histones / ultrastructure
  • Humans
  • Models, Molecular
  • Molecular Weight
  • Nucleosomes / chemistry
  • Nucleosomes / genetics
  • Nucleosomes / ultrastructure*
  • Protein Processing, Post-Translational / genetics*

Substances

  • Chromatin
  • Histones
  • Nucleosomes
  • DNA