Small multidrug resistance plasmids in Actinobacillus porcitonsillarum

Denise Matter; Alexandra Rossano; Sandra Sieber; Vincent Perreten

doi:10.1016/j.plasmid.2007.11.003

Small multidrug resistance plasmids in Actinobacillus porcitonsillarum

Plasmid. 2008 Mar;59(2):144-52. doi: 10.1016/j.plasmid.2007.11.003. Epub 2008 Jan 10.

Authors

Denise Matter¹, Alexandra Rossano, Sandra Sieber, Vincent Perreten

Affiliation

¹ Institute of Veterinary Bacteriology, University of Berne, Länggass-Strasse 122, Postfach, CH-3001 Bern, Switzerland.

PMID: 18190962
DOI: 10.1016/j.plasmid.2007.11.003

Abstract

The complete nucleotide sequences of six Actinobacillus porcitonsillarum plasmids pKMA202 (13.425-kb), pKMA1467 (11.115-kb), pKMA5 (9.549-kb), pIMD50 (8.751-kb), pKMA505 (8.632-kb) and pKMA757 (4.556-kb) and three Actinobacillus pleuropneumoniae plasmids pPSAS1522 (4.244-kb), pARD3079 (3.884-kb) and pKMA2425 (3.156-kb) were determined. All the plasmids contain the sulfonamide resistance gene sul2. One A. pleuropneumoniae plasmid and five A. porcitonsillarum plasmids also have the streptomycin resistance gene strA. Among these latter five A. porcitonsillarum plasmids, four also harbor the beta-lactam resistance gene bla(ROB-1). This study is the first report of multidrug resistance plasmids in the non-pathogenic A. porcitonsillarum.

MeSH terms

Actinobacillus / genetics*
Actinobacillus / metabolism*
Base Sequence
Cluster Analysis
Drug Resistance, Microbial
Drug Resistance, Multiple*
Physical Chromosome Mapping
Plasmids / genetics
Plasmids / metabolism*