Abstract
Bacterial sigma (sigma) factors confer gene specificity upon the RNA polymerase, the central enzyme that catalyses gene transcription. The binding of the alternative sigma factor sigma(54) confers upon the RNA polymerase special functional and regulatory properties, making it suited for control of several major adaptive responses. Here, we summarize our current understanding of the interactions the sigma(54) factor makes with the bacterial transcription machinery.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Bacteria / enzymology
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Bacteria / genetics
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Bacteria / metabolism*
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DNA-Directed RNA Polymerases / chemistry*
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DNA-Directed RNA Polymerases / metabolism*
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Promoter Regions, Genetic*
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RNA Polymerase Sigma 54 / chemistry*
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RNA Polymerase Sigma 54 / metabolism
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RNA, Bacterial / genetics
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Transcription, Genetic*
Substances
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RNA, Bacterial
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DNA-Directed RNA Polymerases
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RNA Polymerase Sigma 54