Swelfe: a detector of internal repeats in sequences and structures

Bioinformatics. 2008 Jul 1;24(13):1536-7. doi: 10.1093/bioinformatics/btn234. Epub 2008 May 16.

Abstract

Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid sequences and in 3D structures using dynamic programming. The associated web server also shows the relationships between repeats at each level and facilitates visualization of the results.

Availability: http://bioserv.rpbs.jussieu.fr/swelfe.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Internet*
  • Repetitive Sequences, Nucleic Acid / genetics*
  • Sequence Alignment / methods*
  • Sequence Analysis / methods*
  • Software*