HELIQUEST: a web server to screen sequences with specific alpha-helical properties

Romain Gautier; Dominique Douguet; Bruno Antonny; Guillaume Drin

doi:10.1093/bioinformatics/btn392

HELIQUEST: a web server to screen sequences with specific alpha-helical properties

Bioinformatics. 2008 Sep 15;24(18):2101-2. doi: 10.1093/bioinformatics/btn392. Epub 2008 Jul 28.

Authors

Romain Gautier¹, Dominique Douguet, Bruno Antonny, Guillaume Drin

Affiliation

¹ Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice Sophia Antipolis and CNRS, Valbonne, France. gautier@ipmc.cnrs.fr

PMID: 18662927
DOI: 10.1093/bioinformatics/btn392

Abstract

Summary: HELIQUEST calculates the physicochemical properties and amino acid composition of an alpha-helix and screens databank to identify protein segments possessing similar features. This server is also dedicated to mutating helices manually or automatically by genetic algorithm to design analogues of defined features.

Availability: http://heliquest.ipmc.cnrs.fr.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computer Simulation
Databases, Protein
Internet
Models, Biological
Protein Structure, Secondary*
Proteins / chemistry
Sequence Analysis, Protein / methods*
Software*
User-Computer Interface

Substances

Proteins