DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

Bioinformatics. 2010 Jan 1;26(1):136-8. doi: 10.1093/bioinformatics/btp612. Epub 2009 Oct 24.

Abstract

Summary: High-throughput RNA sequencing (RNA-seq) is rapidly emerging as a major quantitative transcriptome profiling platform. Here, we present DEGseq, an R package to identify differentially expressed genes or isoforms for RNA-seq data from different samples. In this package, we integrated three existing methods, and introduced two novel methods based on MA-plot to detect and visualize gene expression difference.

Availability: The R package and a quick-start vignette is available at http://bioinfo.au.tsinghua.edu.cn/software/degseq

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Base Sequence
  • Gene Expression Profiling / methods*
  • Molecular Sequence Data
  • Oligonucleotide Array Sequence Analysis / methods*
  • Programming Languages*
  • RNA / genetics*
  • Sequence Analysis, RNA / methods*
  • Software*

Substances

  • RNA