Bupropion for the treatment of neuropathic pain

Am J Hosp Palliat Care. 2010 Aug;27(5):333-6. doi: 10.1177/1049909110361229. Epub 2010 Feb 24.

Abstract

Neuropathic pain is a common problem in clinical practice, affecting patients physically, emotionally, financially, and socially. Current treatment includes antidepressants, antiepileptics, and opioid analgesics. Bupropion is a specific inhibitor of neuronal noradrenaline reuptake and a weak inhibitor of dopamine reuptake, which shows some promise in the treatment of neuropathic pain.

Publication types

  • Review

MeSH terms

  • Analgesics, Non-Narcotic / therapeutic use
  • Bupropion / therapeutic use*
  • Chronic Disease
  • Controlled Clinical Trials as Topic
  • Dopamine Uptake Inhibitors / therapeutic use*
  • Humans
  • Neuralgia / drug therapy*
  • Neurotransmitter Uptake Inhibitors / therapeutic use*
  • Pain / drug therapy
  • Palliative Care / methods
  • Treatment Outcome

Substances

  • Analgesics, Non-Narcotic
  • Dopamine Uptake Inhibitors
  • Neurotransmitter Uptake Inhibitors
  • Bupropion