Investigating neuronal activity by SPYCODE multi-channel data analyzer

Neural Netw. 2010 Aug;23(6):685-97. doi: 10.1016/j.neunet.2010.05.002. Epub 2010 May 12.

Abstract

Multi-channel acquisition from neuronal networks, either in vivo or in vitro, is becoming a standard in modern neuroscience in order to infer how cell assemblies communicate. In spite of the large diffusion of micro-electrode-array-based systems, researchers usually find it difficult to manage the huge quantity of data routinely recorded during the experimental sessions. In fact, many of the available open-source toolboxes still lack two fundamental requirements for treating multi-channel recordings: (i) a rich repertoire of algorithms for extracting information both at a single channel and at the whole network level; (ii) the capability of autonomously repeating the same set of computational operations to 'multiple' recording streams (also from different experiments) and without a manual intervention. The software package we are proposing, named SPYCODE, was mainly developed to respond to the above constraints and generally to offer the scientific community a 'smart' tool for multi-channel data processing.

MeSH terms

  • Action Potentials / physiology
  • Animals
  • Cells, Cultured
  • Electrophysiology / instrumentation
  • Electrophysiology / methods*
  • Electrophysiology / trends
  • Humans
  • Nerve Net / physiology*
  • Neurons / physiology*
  • Neurophysiology / instrumentation
  • Neurophysiology / methods
  • Neurophysiology / trends
  • Rats
  • Rats, Sprague-Dawley
  • Signal Processing, Computer-Assisted*
  • Software / trends*