The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA

Angew Chem Int Ed Engl. 2010 Nov 15;49(47):8885-8. doi: 10.1002/anie.201001242.
No abstract available

Publication types

  • Research Support, American Recovery and Reinvestment Act
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AlkB Homolog 8, tRNA Methyltransferase
  • Anticodon
  • Base Sequence
  • Catalysis
  • DNA Repair
  • Humans
  • Hydroxylation
  • Methylation
  • Protein Structure, Tertiary
  • RNA, Transfer / chemistry*
  • RNA, Transfer / genetics
  • Uridine / analogs & derivatives*
  • Uridine / chemistry
  • tRNA Methyltransferases / chemistry*

Substances

  • Anticodon
  • 5-methoxycarbonylmethyluridine
  • RNA, Transfer
  • ALKBH8 protein, human
  • AlkB Homolog 8, tRNA Methyltransferase
  • tRNA Methyltransferases
  • Uridine