First outbreak of methicillin-resistant Staphylococcus aureus USA300 harboring the Panton-Valentine leukocidin genes among Japanese health care workers and hospitalized patients

Miki Nagao; Yoshitsugu Iinuma; Masahiro Suzuki; Aki Matsushima; Shunji Takakura; Yutaka Ito; Satoshi Ichiyama

doi:10.1016/j.ajic.2010.04.214

First outbreak of methicillin-resistant Staphylococcus aureus USA300 harboring the Panton-Valentine leukocidin genes among Japanese health care workers and hospitalized patients

Am J Infect Control. 2010 Nov;38(9):e37-9. doi: 10.1016/j.ajic.2010.04.214. Epub 2010 Sep 6.

Authors

Miki Nagao¹, Yoshitsugu Iinuma, Masahiro Suzuki, Aki Matsushima, Shunji Takakura, Yutaka Ito, Satoshi Ichiyama

Affiliation

¹ Department of Infection Control and Prevention, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Kyoto, Japan. mnagao@kuhp.kyoto-u.ac.jp

PMID: 20822831
DOI: 10.1016/j.ajic.2010.04.214

Abstract

This report describes the first outbreak of methicillin-resistant Staphylococcus aureus USA300 in a general hospital ward in Japan, involving 6 health care workers and 4 patients. This report emphasizes the need for health care personnel to be alert that methicillin-resistant Staphylococcus aureus harboring Panton-Valentine leukocidin gene poses a threat for both nosocomial and occupational infection.

MeSH terms

Adolescent
Adult
Aged
Bacterial Toxins / genetics*
Bacterial Typing Techniques
Cross Infection / epidemiology*
Cross Infection / microbiology
DNA Fingerprinting
Disease Outbreaks*
Exotoxins / genetics*
Female
Genotype
Health Personnel*
Humans
Japan / epidemiology
Leukocidins / genetics*
Male
Methicillin-Resistant Staphylococcus aureus / classification*
Methicillin-Resistant Staphylococcus aureus / genetics
Methicillin-Resistant Staphylococcus aureus / isolation & purification
Staphylococcal Infections / epidemiology*
Staphylococcal Infections / microbiology
Virulence Factors / genetics*

Substances

Bacterial Toxins
Exotoxins
Leukocidins
Panton-Valentine leukocidin
Virulence Factors