Insect glutathione transferases

Drug Metab Rev. 2011 May;43(2):253-65. doi: 10.3109/03602532.2011.552911. Epub 2011 Feb 17.

Abstract

This article is an overview of the current knowledge of insect glutathione transferases. Three major topics are discussed: the glutathione transferase contributions to insecticide resistance, the polymorphic nature of the insect glutathione transferase superfamily, and a summary of the current structure-function studies on insect glutathione transferases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Glutathione Transferase* / chemistry
  • Glutathione Transferase* / genetics
  • Glutathione Transferase* / metabolism
  • Glutathione Transferase* / physiology
  • Humans
  • Insecta / enzymology*
  • Insecticide Resistance
  • Models, Molecular
  • Molecular Sequence Data
  • Phylogeny
  • Protein Conformation
  • Sequence Alignment

Substances

  • Glutathione Transferase