The domestic dog: man's best friend in the genomic era

Genome Biol. 2011;12(2):216. doi: 10.1186/gb-2011-12-2-216. Epub 2011 Feb 22.

Abstract

The domestic dog genome--shaped by domestication, adaptation to human-dominated environments and artificial selection--encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Animals, Domestic / genetics*
  • Breeding
  • Chromosome Mapping
  • Dogs / genetics*
  • Genetic Variation
  • Genome*
  • Genome-Wide Association Study
  • Genomics / methods*
  • Genotype
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Phenotype
  • Phylogeny
  • Phylogeography
  • Polymorphism, Single Nucleotide
  • Quantitative Trait, Heritable
  • Selection, Genetic