The evidence for the role of transforming growth factor-beta in the formation of abnormal scarring

Int Wound J. 2011 Jun;8(3):218-23. doi: 10.1111/j.1742-481X.2011.00771.x. Epub 2011 Mar 30.

Abstract

The complex biological and physiological mechanisms that result in poor quality scarring are still not fully understood. This review looks at current evidence of the role of transforming growth factor-beta (TGFβ) in this pathological process.

Publication types

  • Review

MeSH terms

  • Biomarkers / metabolism
  • Cicatrix / metabolism
  • Cicatrix, Hypertrophic / metabolism*
  • Female
  • Humans
  • Keloid / metabolism*
  • Male
  • Risk Factors
  • Transforming Growth Factor beta / metabolism*
  • Wound Healing / physiology*

Substances

  • Biomarkers
  • Transforming Growth Factor beta