Tracing cells for tracking cell lineage and clonal behavior

Margaret E Buckingham; Sigolène M Meilhac

doi:10.1016/j.devcel.2011.07.019

Tracing cells for tracking cell lineage and clonal behavior

Dev Cell. 2011 Sep 13;21(3):394-409. doi: 10.1016/j.devcel.2011.07.019.

Authors

Margaret E Buckingham¹, Sigolène M Meilhac

Affiliation

¹ Molecular Genetics of Development Unit, CNRS URA 2578, Department of Developmental Biology, Institut Pasteur, Paris, France. margaret.buckingham@pasteur.fr

PMID: 21920310
DOI: 10.1016/j.devcel.2011.07.019

Abstract

Reconstructing the lineage of cells is central to understanding development and is now also an important issue in stem cell research. Technological advances in genetically engineered permanent cell labeling, together with a multiplicity of fluorescent markers and sophisticated imaging, open new possibilities for prospective and retrospective clonal analysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Lineage*
Cell Tracking / methods*
Chick Embryo
Clone Cells
Drosophila / cytology
Drosophila Proteins / chemistry
Humans
Mice
Mosaicism
Stem Cell Research

Substances

Drosophila Proteins