Abstract
Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Differentiation / genetics*
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Enhancer Elements, Genetic*
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Epigenesis, Genetic
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Gene Expression Regulation, Developmental*
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Genome
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Genome-Wide Association Study
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Humans
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Transcription, Genetic