Sorting cells by size, shape and deformability

Lab Chip. 2012 Mar 21;12(6):1048-51. doi: 10.1039/c2lc21083e. Epub 2012 Feb 10.

Abstract

While size has been widely used as a parameter in cellular separations, in this communication we show how shape and deformability, a mainly untapped source of specificity in preparative and analytical microfluidic devices can be measured and used to separate cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Separation / instrumentation*
  • Cell Separation / methods
  • Cell Size
  • Erythrocyte Deformability
  • Erythrocytes / cytology*
  • Humans
  • Microfluidic Analytical Techniques / instrumentation*
  • Microfluidic Analytical Techniques / methods