Drosophila: a model for understanding obesity and diabetic complications

Exp Clin Endocrinol Diabetes. 2012 Apr;120(4):184-5. doi: 10.1055/s-0032-1304566. Epub 2012 Mar 8.

Abstract

The molecular mechanisms underlying development of obesity and diabetic complications are not well understood. Drosophila has become a popular model organism for studying a variety of human diseases. We discuss here emerging Drosophila models of obesity and diabetic complications.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Genetically Modified
  • Comprehension / physiology
  • Diabetes Complications / etiology*
  • Diabetes Complications / genetics
  • Diabetes Complications / pathology
  • Diabetes Complications / physiopathology
  • Dietary Carbohydrates / pharmacology
  • Disease Models, Animal*
  • Drosophila / genetics
  • Drosophila / physiology*
  • Heart / drug effects
  • Heart / physiology
  • Humans
  • Neurons / drug effects
  • Neurons / physiology
  • Obesity / etiology*
  • Obesity / genetics
  • Obesity / pathology
  • Obesity / physiopathology

Substances

  • Dietary Carbohydrates