Abstract
The Martini model, a coarse-grained force field for biomolecular simulations, has found a broad range of applications since its release a decade ago. Based on a building block principle, the model combines speed and versatility while maintaining chemical specificity. Here we review the current state of the model. We describe recent highlights as well as shortcomings, and our ideas on the further development of the model.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Drug Carriers / chemistry
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Gene Transfer Techniques
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Lipid Bilayers / chemistry
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Lipoproteins / chemistry
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Lipoproteins / metabolism
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Membrane Proteins / chemistry
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Membrane Proteins / metabolism
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Models, Theoretical*
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Molecular Dynamics Simulation
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Nanoparticles / chemistry
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Peptides / chemistry
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Peptides / metabolism
Substances
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Drug Carriers
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Lipid Bilayers
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Lipoproteins
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Membrane Proteins
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Peptides