The Brucella pathogens are polarized bacteria

Microbes Infect. 2013 Dec;15(14-15):998-1004. doi: 10.1016/j.micinf.2013.10.008. Epub 2013 Oct 18.

Abstract

Brucella pathogens are responsible for brucellosis, a worldwide zoonosis. They are facultative intracellular pathogens characterized by their asymmetric division and their unipolar growth. This growth modality generates poles with specialized functions (through polar recruitment of polar adhesins or of cell cycle regulators) and progeny cells with potentially different fates.

Keywords: Adhesion; Brucella; Cell cycle; Growth; Host–pathogen interaction; Polarity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adhesins, Bacterial
  • Animals
  • Asymmetric Cell Division
  • Bacterial Proteins / metabolism
  • Brucella / classification
  • Brucella / physiology*
  • Brucellosis / microbiology
  • Cell Cycle
  • DNA Repair
  • Flagella / physiology
  • Host-Pathogen Interactions
  • Humans

Substances

  • Adhesins, Bacterial
  • Bacterial Proteins