Methotrexate: new uses for an old drug

Philip J Hashkes; Mara L Becker; David A Cabral; Ronald M Laxer; Amy S Paller; C Egla Rabinovich; Dan Turner; Francesco Zulian

doi:10.1016/j.jpeds.2013.10.029

Methotrexate: new uses for an old drug

J Pediatr. 2014 Feb;164(2):231-6. doi: 10.1016/j.jpeds.2013.10.029. Epub 2013 Nov 25.

Authors

Philip J Hashkes¹, Mara L Becker², David A Cabral³, Ronald M Laxer⁴, Amy S Paller⁵, C Egla Rabinovich⁶, Dan Turner⁷, Francesco Zulian⁸

Affiliations

¹ Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel. Electronic address: hashkesp@szmc.org.il.
² Division of Pediatric Rheumatology, Children's Mercy Hospitals and Clinics, Kansas City, MO.
³ Division of Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
⁴ Division of Rheumatology, The Hospital for Sick Children, Departments of Pediatrics and Medicine, University of Toronto, Toronto, ON, Canada.
⁵ Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.
⁶ Division of Pediatric Rheumatology, Duke University, Durham, NC.
⁷ Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel.
⁸ Department of Pediatrics, University of Padua, Padua, Italy.

PMID: 24286573
DOI: 10.1016/j.jpeds.2013.10.029

No abstract available

Keywords: AICAR; Amino-imidazole carboxamide ribonucleotide; CD; Crohn's disease; GPA; Granulomatosis with polyangiitis; IBD; Inflammatory bowel disease; JIA; Juvenile idiopathic arthritis; MRP; MTX; Methotrexate; Myeloid-related protein; SNP; Single nucleotide polymorphism.

Publication types

Review

MeSH terms

Antirheumatic Agents / therapeutic use
Arthritis, Juvenile / drug therapy*
Humans
Methotrexate / therapeutic use*
Treatment Outcome

Substances

Antirheumatic Agents
Methotrexate