Working together: basal ganglia pathways in action selection

Trends Neurosci. 2014 Jun;37(6):301-3. doi: 10.1016/j.tins.2014.04.004. Epub 2014 May 9.

Abstract

Jin, Tecuapetla, and Costa combined in vivo electrophysiology with optogenetic-identification to examine firing in multiple basal ganglia nuclei during rapid motor sequences. Their results support a model of basal ganglia function in which co-activation of the direct and indirect pathways facilitate appropriate, while inhibiting competing, motor programs.

Publication types

  • Review

MeSH terms

  • Animals
  • Basal Ganglia / physiology*
  • Brain / physiology
  • Learning / physiology*
  • Mice
  • Motor Activity / physiology*
  • Neural Pathways / physiology
  • Optogenetics