CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W119-23. doi: 10.1093/nar/gku359. Epub 2014 May 16.

Abstract

CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the existing tool IntaRNA (Interacting RNAs) in order to predict targets, interaction domains and consequently the regulatory networks of bacterial small RNA molecules. The CopraRNA prediction results are accompanied by extensive postprocessing methods such as functional enrichment analysis and visualization of interacting regions. Here, we introduce the functionality of the CopraRNA and IntaRNA webservers and give detailed explanations on their postprocessing functionalities. Both tools are freely accessible at http://rna.informatik.uni-freiburg.de.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Gene Regulatory Networks
  • Internet
  • RNA, Bacterial / chemistry*
  • RNA, Bacterial / metabolism*
  • RNA, Small Untranslated / chemistry*
  • RNA, Small Untranslated / metabolism*
  • Sequence Analysis, RNA
  • Software*

Substances

  • RNA, Bacterial
  • RNA, Small Untranslated