Geroscience: linking aging to chronic disease

Cell. 2014 Nov 6;159(4):709-13. doi: 10.1016/j.cell.2014.10.039.

Abstract

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk factor for a majority of chronic diseases driving both morbidity and mortality, it is critical to expand geroscience research directed at extending human healthspan.

MeSH terms

  • Aging / pathology
  • Aging / physiology*
  • Animals
  • Biomedical Research
  • Chronic Disease*
  • Epigenesis, Genetic
  • Gene-Environment Interaction
  • Humans