Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

Alzheimers Dement. 2015 Jun;11(6):710-7. doi: 10.1016/j.jalz.2014.10.008. Epub 2014 Dec 12.

Abstract

Scientific evidence continues to demonstrate the linkage of vascular contributions to cognitive impairment and dementia such as Alzheimer's disease. In December, 2013, the Alzheimer's Association, with scientific input from the National Institute of Neurological Disorders and Stroke and the National Heart, Lung and Blood Institute from the National Institutes of Health, convened scientific experts to discuss the research gaps in our understanding of how vascular factors contribute to Alzheimer's disease and related dementia. This manuscript summarizes the meeting and the resultant discussion, including an outline of next steps needed to move this area of research forward.

Keywords: Alzheimer's disease; Animal models; Biomarkers; Dementia; Small vessel disease; Vascular dementia.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / blood supply
  • Brain / physiopathology
  • Cerebrovascular Disorders / physiopathology*
  • Cognition Disorders / physiopathology*
  • Congresses as Topic
  • Dementia / physiopathology*
  • Humans
  • National Heart, Lung, and Blood Institute (U.S.)
  • National Institute of Neurological Disorders and Stroke (U.S.)
  • Societies
  • United States