Clinical practice. Uterine fibroids

N Engl J Med. 2015 Apr 23;372(17):1646-55. doi: 10.1056/NEJMcp1411029.

Abstract

A 47-year-old black woman has heavy menstrual bleeding and iron-deficiency anemia.She reports nocturia and urinary frequency. A colonoscopy is negative. Ultrasonography shows a modestly enlarged uterus with three uterine fibroids. She is not planning to become pregnant. How should this case be evaluated and managed?

Publication types

  • Review

MeSH terms

  • Contraceptives, Oral, Hormonal / therapeutic use*
  • Female
  • Gonadotropin-Releasing Hormone / agonists
  • Humans
  • Hysterectomy*
  • Leiomyoma / diagnosis
  • Leiomyoma / drug therapy*
  • Leiomyoma / surgery*
  • Practice Guidelines as Topic
  • Progesterone / antagonists & inhibitors
  • Uterine Artery Embolization*
  • Uterine Myomectomy*
  • Uterine Neoplasms / diagnosis
  • Uterine Neoplasms / drug therapy*
  • Uterine Neoplasms / surgery*

Substances

  • Contraceptives, Oral, Hormonal
  • Gonadotropin-Releasing Hormone
  • Progesterone