Mitochondrial genome evolution in yeasts: an all-encompassing view

FEMS Yeast Res. 2015 Jun;15(4):fov023. doi: 10.1093/femsyr/fov023. Epub 2015 May 11.

Abstract

Mitochondria are important organelles that harbor their own genomes encoding a key set of proteins that ensure respiration and provide the eukaryotic cell with energy. Recent advances in high-throughput sequencing technologies present a unique opportunity to explore mitochondrial (mt) genome evolution. The Saccharomycotina yeasts have proven to be the leading organisms for mt comparative and population genomics. In fact, the explosion of complete yeast mt genome sequences has allowed for a broader view of the mt diversity across this incredibly diverse subphylum, both within and between closely related species. Here, we summarize the present state of yeast mitogenomics, including the currently available data and what it reveals concerning the diversity of content, organization, structure and evolution of mt genomes.

Keywords: genomics; mitochondrial genomes; population genomics; yeast.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Evolution, Molecular*
  • Genetic Variation*
  • Genome, Mitochondrial*
  • Genomics
  • Yeasts / genetics*