LncReg: a reference resource for lncRNA-associated regulatory networks

Zhong Zhou; Yi Shen; Muhammad Riaz Khan; Ao Li

doi:10.1093/database/bav083

LncReg: a reference resource for lncRNA-associated regulatory networks

Database (Oxford). 2015 Sep 10:2015:bav083. doi: 10.1093/database/bav083. Print 2015.

Authors

Zhong Zhou¹, Yi Shen¹, Muhammad Riaz Khan², Ao Li³

Affiliations

¹ School of Information Science and Technology, Centers for Biomedical Engineering and.
² School of Life Science, University of Science and Technology of China, 443 Huangshan Road, Hefei 230027, China.
³ School of Information Science and Technology, Centers for Biomedical Engineering and aoli@ustc.edu.cn.

Abstract

Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads to complexity of literature about particular lncRNAs. Therefore, for the convenience of the researchers, we collected regulatory relationships of the lncRNAs and built a database called 'LncReg'. This database is developed by collecting 1081 validated lncRNA-associated regulatory entries, including 258 non-redundant lncRNAs and 571 non-redundant genes. With regulatory relationships information, LncReg can provide overall perspectives of regulatory networks of lncRNAs and comprehensive data for bioinformatics research, which is useful for understanding the functional roles of lncRNAs. Database URL: http://bioinformatics.ustc.edu.cn/lncreg/.

Publication types

Dataset
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Databases, Nucleic Acid*
Gene Regulatory Networks*
Mice
RNA, Long Noncoding / biosynthesis*
RNA, Long Noncoding / genetics*

Substances

RNA, Long Noncoding