RNALocate: a resource for RNA subcellular localizations

Ting Zhang; Puwen Tan; Liqiang Wang; Nana Jin; Yana Li; Lin Zhang; Huan Yang; Zhenyu Hu; Lining Zhang; Chunyu Hu; Chunhua Li; Kun Qian; Changjian Zhang; Yan Huang; Kongning Li; Hao Lin; Dong Wang

doi:10.1093/nar/gkw728

RNALocate: a resource for RNA subcellular localizations

Nucleic Acids Res. 2017 Jan 4;45(D1):D135-D138. doi: 10.1093/nar/gkw728. Epub 2016 Aug 19.

Authors

Ting Zhang¹, Puwen Tan¹, Liqiang Wang¹, Nana Jin¹, Yana Li¹, Lin Zhang¹, Huan Yang², Zhenyu Hu¹, Lining Zhang¹, Chunyu Hu¹, Chunhua Li¹, Kun Qian¹, Changjian Zhang², Yan Huang¹, Kongning Li³, Hao Lin⁴, Dong Wang^{5

6}

Affiliations

¹ College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
² Key Laboratory for NeuroInformation of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
³ College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China kongningli@hotmail.com.
⁴ Key Laboratory for NeuroInformation of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China hlin@uestc.edu.cn.
⁵ College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China wangdong@ems.hrbmu.edu.cn.
⁶ Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China.

Abstract

Increasing evidence has revealed that RNA subcellular localization is a very important feature for deeply understanding RNA's biological functions after being transported into intra- or extra-cellular regions. RNALocate is a web-accessible database that aims to provide a high-quality RNA subcellular localization resource and facilitate future researches on RNA function or structure. The current version of RNALocate documents more than 37 700 manually curated RNA subcellular localization entries with experimental evidence, involving more than 21 800 RNAs with 42 subcellular localizations in 65 species, mainly including Homo sapiens, Mus musculus and Saccharomyces cerevisiae etc. Besides, RNA homology, sequence and interaction data have also been integrated into RNALocate. Users can access these data through online search, browse, blast and visualization tools. In conclusion, RNALocate will be of help in elucidating the entirety of RNA subcellular localization, and developing new prediction methods. The database is available at http://www.rna-society.org/rnalocate/.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Computational Biology / methods*
Databases, Nucleic Acid*
Humans
Intracellular Space
RNA Transport*
RNA*
Web Browser

Substances

RNA